Synthesis and antioxidant activity of dioxazaphosphinin-2-ones
نویسندگان
چکیده
A simple and efficient synthesis of dioxazaphosphinin-2-ones has been developed by the cyclisation of 2-hydroxy-1,2-diphenylethanoneoxime with phosphorus oxychloride in the presence of triethylamine in dry THF to afford the corresponding monochloride. In the next step, subsequent reaction of monochloride with different amines at 50-60 ̊C for 2-3 hours resulted in the formation of the title compounds (4a-j). The lead compounds were screened for their antioxidant activity.
منابع مشابه
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